![]() ![]() Although, I used it only for modeling until now, I am totally satisfied with it. ![]() It is a great software to design any 3D model to print, but it has many other features too (e.g. Although they are not professional plans, I will show and introduce them shortly below. I made a draft on paper for both versions. It will be much easier to design it with a CAD software based on the draft. It doesn’t matter if the scale factors are not so precise, the goal is to know what you need exactly at the end. This way you don’t have to measure and calculate during design phase again and again. Measure all the necessary sizes and record them on the paper. The original plan that requires these components, the automated watering system is not done yet but I’m sure that I will introduce it in another post as soon as I finish it.įor me it always helps to create a draft on paper before I start to design anything. But the creation steps are similar for both ideas. My second idea has more possibilities and is easier to create and control, so I describe it in details after that. I also made a video for that, which contains a step-by-step guide. Since my first idea has some limitations and is not so cheap, I will introduce it in short first. Besides the micro servo I don’t need any special component, only a 3D printer. Above of that it is cheap, easy to control and makes able to provide multiple outputs with only one servo. It could rotate a 3D printed shape, that allows to flow the water in one direction only, and blocks other outputs. Idea 2: My second idea (2nd image) was to use a small micro servo. But if you need to have only a few outputs (2 or 3), it might be a good choice. Although it worked and looked much more scientific, but had some limitations and was not so cheap if I wanted to have many outputs. Idea 1: My first idea (1st image) was to use a small magnet, and move it with electromagnets. Somehow I have to make free only one path of the water, and block all the others, so I need something that is electrically movable. If more plants need water at the same time, others can wait some seconds :). This way I will be able to select a plant (that actually needs water), and watering only that one. It makes able to control the path of the water, by electrically selecting one output from many, on that the water will go out. I need a device (or more), that has one input on that the water comes in, and as many outputs as many plant pots I have. ![]()
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It will take all that and a whole lot more to get where we need to go. To heal our broken communities we’ll need symbolic acts and lots of teach-ins, but also sustained, organized action for years to come. Then we watched an eye-opening documentary about the mass eviction of people of color from Marine Drive Apartments. Housing advocate and attorney Grace Andriette talked about the history of segregation in a place where we could look out the window and see Buffalo’s segregation line, Main Street. ![]() My favorite was the one about housing segregation at HOME’s then-new home on Ferry Street at Main. One of the lesser-remembered aspects of Hands Across Buffalo was the set of teach-ins conducted that day, and for a time after. Teach-ins from Hands Across Buffalo (2014) And this time, instead of a one-and-done, perhaps we need to do it more regularly, to remind us all that the issue is still here and isn’t fixed yet – until, someday, it is.Īnd also this time – perhaps – as a collective expression of determination not to let what happened define us, divide us, or discourage us. So what role could a symbolic gesture like Hands Across Buffalo play in that? While clearly not enough – as it wasn’t eight years ago – it seems to me, when the time is right, it could help. And those of us who really understand just how bad the segregation in Buffalo is, yet managed to accommodate ourselves to it and continued to go about our lives. Including those who went to brunch Sunday morning the same as every weekend as if nothing had happened. Because it is not just those whose family and friends and neighbors were shot who will need healing, but all of us. A better day for the east side, for sure. If that sounds a little bitter to you, thanks for noticing.īut some day – who knows when – the time will come to try to see through the hurt and rage and cynicism to find a path forward to a better day. So if your propaganda-poisoned mind decides it’s time to go hunt Black people, where do you go? The one store they will all be at. ![]() An entire half of the second-largest city in New York State has but one full-service supermarket. ![]() The “Mississippi of the North” is how Organizer Dakarai Singletary put it in this article.Īnd it’s not just a modern-day settlement apartheid, but an economic apartheid and a food apartheid as well. What is shows clearly is that a century and a half after the end of the Civil War, a cause in which many Buffalonians gave “the last full measure of devotion,” Buffalo is one of the most structurally segregated places outside of South Africa. At the risk of giving any credit at all to that domestic terrorist whose world view was so twisted and thoughts were so consumed by hate, although tragically deluded he was no dummy.įrom all the way across the state, as the Buffalo News’ Caitlin Dewey described in chilling detail, the murderer methodically used the very same information our leaders and public officials have been able to see for decades. ![]() ![]() ![]() ![]() But I’ve had to face the fact that I’ll never be able to focus on any one subject long enough to make a blog about it a success. Over the years I’ve dabbled in blogs on various topics: Lytro cameras, food, self-sustaining urban lifetsyle, Automator for Mac, iOS photography, short stories, etc. Byword can also send HTML-formatted emails or create PDFs. (Currently Squarespace is not supported for direct publishing, but Byword Markdown can be pasted into the Squarespace editor.) HTML docs can be created directly in Byword for uploading anywhere on the web. Publishing with a tap.īyword can publish directly to content management systems with APIs like WordPress, Medium, Tumblr. Byword adds features that Markdown users value most, like publishing to all the major blogging platforms and recognizing the syntax of various flavors of Markdown, like the recent addition of support for opening R Markdown docs (that incorporate data charts written in plain text). The Metaclassy dev team in Coimbra, Portugal (vao Briosa) focuses on just this one product and adds core function and OS compatibility, not bells and whistles that often just get in the way of writing and editing. But then, it doesn’t really need to develop quickly, since Markdown hasn’t changed since 2004. Unlike Bear, Ulysses and Agenda, Byword doesn’t have an aggressive development roadmap. Shortcuts to create and open recent documents by holding the icon on home screen.Handling of multiple content storage platforms at the same time.Stable syncing across iPad, iPhone and Mac.It gives you the productivity that Markdown was intended for. Byword both writes and reads exceptionally well, minimizing the need for ever calling up a preview (which you simply do by swiping left). At the same time, link-and-image-tag shorthand is completely visible, making editing complex tags much easier. Shorthand characters like # and * get grayed out, but the text associated with them (like headers and emphasized text) gets bolded or italicized. Byword’s greatest strength is its syntax highlighting that makes it easy to read what you’ve written. Byword remains the most functional app for writing and editing Markdown.Ĭompared to the Ulysses, Bear and Agenda hybrids, Byword is a spartan text editor, but highly functional and targeted at web publishing. text to the URL, you can see how he formatted the page. His page is written in Markdown and if you add. Creator John Gruber has a Markdown Syntax Page that shows the basics. Markdown has many converts looking for an easier way to do both HTML and rich-text formatting. Most Markdown writers just find it easier to not have to stop typing to format.) (If you like WYSIWYG formatting Byword does have the basic keypresses and menu-bar formatting for Markdown available. You just type a simple asterisk before and after a word and it’s italicized. And unlike raw HTML, no more typing and then. No complex keypresses to remember like Control-I to start an emphasized word and then another Control-I to end it. No highlighting a word and choosing italic from a menu. Why the popularity of Markdown? Many of those who write or take copious notes have found Markdown such a stress-relieving and productive change from the formatting nightmares of word processing: You just type. (These are hybrids that use Markdown for formatting, but automatically render tags to look more like Word.) There are over 100 Markdown editors in the App Store, so I’m sure you’ll find one that fits your workflow. Markdown has proven itself in the note-taking space too with popular apps like Ulysses, Bear and Agenda. How big is it? Reddit and GitHub both use Markdown. Over the past 16 years, adoption of Markdown has been massive, since it makes web writing possible without knowing code and without having to overly think and apply formatting (like with Word). Blogging killed the analog newspaper and magazine, while laying the foundation for online reporting. You can embed a video, but it’s impractical to try to make a post into a video. You can embed a tweet in a post, but you can’t put a full post in a tweet. The strength is that web articles can embed all the other formats. Blogging grew up to became web news writing and, more than ever, is a vital piece of the content ecosystem. This article shows you how to use Byword, an iOS, iPadOS and Mac OS text editor that was built for writing in Markdown, with a preview and instant publishing to most blogs and content management systems, like WordPress and Medium.Ĭontrary to what the so-called experts may say, blogging is not dead. Most web writers writer in Markdown, an HTML-tag shorthand that’s integrated into most content management systems. Writing specifically for the web is now an old discipline. ![]() ![]() ![]() Footage Music Sound Effects After Effects. Redbubble brings you unique and colorful. In this class, you will learn how to do motion tracking in After Effects. Take up to 50 off After Effects Use code AE50 First Purchase Only. 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You can increase quality using subdivision surface. 7 iPad Pro iPad Air 2020, iPad Air 2 6, 6 Plus, 6S, 6S Plus Medtronic Diabetes Europe. I recently quit my job and returned the work laptops (MacBook Pros) I’ve been using for almost a decade. ![]() ![]() ![]() 6 In the phase III KEYNOTE-040 study, patients with platinum-refractory R/M HNSCC (N = 495) were randomly assigned to pembrolizumab or standard-of-care systemic therapy. 023) and median overall survival (OS) was longer in patients with CPS ≥ 1 than CPS < 1 (10 v 5 months one-sided P =. 10, 11 In the phase Ib KEYNOTE-012 study of pembrolizumab monotherapy in R/M HNSCC (N = 192), objective response rate (ORR) was higher in patients with PD-L1 CPS ≥ 1 than CPS < 1 (21% v 6% one-sided P =. Pembrolizumab produces durable responses and robust antitumor activity in recurrent or metastatic (R/M) HNSCC, with greater benefit observed in PD-L1–enriched populations. The results indicate that although PD-L1 expression is useful, additional predictive biomarkers are needed for informing treatment decisions in low PD-L1–expressing recurrent or metastatic head and neck squamous cell carcinoma. These results support previous findings and demonstrate increased efficacy for pembrolizumab or pembrolizumab-chemotherapy with increasing PD-L1 expression. In the PD-L1 CPS < 1 subgroup, neither pembrolizumab nor pembrolizumab-chemotherapy demonstrated improvement in overall survival compared with cetuximab-chemotherapy. Pembrolizumab and pembrolizumab-chemotherapy demonstrated antitumor activity in the PD-L1 CPS 1-19 subgroup, with pembrolizumab-chemotherapy leading to numerically longer overall survival than cetuximab-chemotherapy. ![]() To further characterize the predictive value of PD-L1 expression, efficacy was analyzed in participants with PD-L1 CPS < 1 and CPS 1-19. Efficacy was assessed in participants with a programmed death ligand-1 (PD-L1) combined positive score (CPS) ≥ 20 and CPS ≥ 1 and the total population. KEYNOTE-048 investigated pembrolizumab monotherapy and pembrolizumab plus chemotherapy in recurrent or metastatic head and neck squamous cell carcinoma. Although expression of PD-L1 is common in HNSCC, some tumors have low or undetectable levels. 5- 7 PD-L1 expression in pembrolizumab trials is described by tumor proportion score (TPS), defined as the percentage of viable tumor cells showing partial or complete membrane PD-L1 staining, or combined positive score (CPS), defined as the number of PD-L1–positive tumor cells, lymphocytes, and macrophages divided by the total number of tumor cells, multiplied by 100. 3, 4 The anti–PD-1 antibodies pembrolizumab and nivolumab have demonstrated antitumor activity and acceptable safety in several cancers that overexpress PD-L1, including HNSCC. 2, 3 PD-1 is expressed on immune cells, including T cells, B cells, and activated monocytes, whereas PD-L1 is expressed by tumor cells, immune cells, and various nonhematopoietic cells. 1 PD-L1 overexpression activates the programmed death 1 (PD-1)/PD-L1 axis to promote immune evasion, permitting tumor growth. Programmed death ligand-1 (PD-L1) is frequently overexpressed in head and neck squamous cell carcinoma (HNSCC) and serves as a therapeutic target and predictive biomarker. Rischin, +17 authors B.1Yale University School of Medicine and Yale Cancer Center, New Haven, CTĢPeter MacCallum Cancer Centre and the University of Melbourne, Melbourne, AustraliaģParacelsus Medical University, Salzburg Cancer Research Institute, and Cancer Cluster Salzburg, Salzburg, AustriaĤCentre Hospitalier de l'Université de Montréal, Montreal, Quebec, CanadaĥNational Cancer Center Hospital East, Kashiwa, JapanĦInstituto do Cancer do Estado de Sao Paulo, Sao Paulo, BrazilħNational Kapodistrian University of Athens, Attikon University Hospital, Athens, GreeceĨVall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, SpainĩUniversity of Kansas Medical Center, Kansas City, KSġ1Medical University of Vienna, Vienna, Austriaġ2Royal Brisbane and Women's Hospital and University of Queensland, Brisbane, Queensland, Australiaġ3Catalan Institute of Oncology, Badalona, Barcelona, Spainġ4Ramathibodi Hospital, Mahidol University, Bangkok, Thailandġ5University Hospital, Zurich, Switzerlandġ6Clinical Oncology Unit, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysiaġ8The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, National Institute for Health Research Biomedical Research Centre, London, United Kingdom Progression after the next line of therapy following pembrolizumab (P) or P plus chemotherapy (P+C) vs EXTREME (E) as first-line (1L) therapy for recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC).},Īuthor=, KEYNOTE-048: Progression after the next line of therapy following pembrolizumab (P) or P plus chemotherapy (P+C) vs EXTREME (E) as first-line (1L) therapy for recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). ![]() ![]() ![]() ![]() Due to their power, Indra offered the Hero Faction's cooperation to Team DxD, however due to their past crimes, the could only be added as provisional reserve members. Due to Cao Cao acting as Indra's vanguard, the Hero Faction became Indra's subordinates. The Hero Faction reformed during the Azazel Cup as Cao Cao once recruited its former members to form Team Spear of the Heavenly Emperor. Jeanne and Heracles were captured by the Devils and Fallen Angels for interrogation, while Siegfried was the only main member of the Hero Faction who died in battle. Indra sends their most powerful members (Cao Cao, Leonardo, and Georg) to the Realm of the Dead, taking all of their Longinus from them. The Hero Faction went inactive after Volume 12 after the loss of their leaders. All of those who didn't reach Balance Breaker were eventually captured and later died as a result of Ophis' snakes destroying their Sacred Gears, while those who did achieve Balance Breaker were called back before they could be caught. Many of these members, however, were sacrificed in battle during the Hero Faction's attempts to force them to achieve Balance Breaker. The Hero Faction possessed a large number of Sacred Gear wielders who were either abducted and brainwashed, or followed willingly. The motto of the Hero Faction was to fight and defeat "evil beings" such as Devils, Fallen Angels, and Dragons that bring harm to Humans. All members of the Hero Faction were either Sacred Gear, Holy Sword, Demon Sword, and/or Longinus wielders. The Hero Faction was one of the factions in Khaos Brigade that consisted of solely Humans. ![]() ![]() ![]() Free trial, lots of fun! Serial Brainsbreaker, free serial brainsbreaker software downloads. It is like playing the classical cardboard jigsaw puzzles and with many advantages. Multifeatured computer jigsaw puzzle for PC and Mac. The program also brainsbreaker puzzles save files in ZIP format brainsbreaker puzzles they can be viewed and restored with most. With BrainsBreaker you can turn any photo into a jigsaw puzzle and also play with the large collection. 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